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Chlordiazepoxide : ウィキペディア英語版 | Chlordiazepoxide
Chlordiazepoxide〔US Patent 2893992〕 , is a sedative/hypnotic drug and benzodiazepine. Chlordiazepoxide was the first benzodiazepine to be synthesized and the discovery of chlordiazepoxide was by pure chance. Chlordiazepoxide and other benzodiazepines were initially accepted with widespread public approval but were followed with widespread public disapproval and recommendations for more restrictive medical guidelines for its use. Chlordiazepoxide has a medium to long half-life but its active metabolite has a very long half-life. The drug has amnestic, anticonvulsant, anxiolytic, hypnotic and skeletal muscle relaxant properties. ==Medical uses== Chlordiazepoxide is indicated for the short-term (2–4 weeks) treatment of anxiety that is severe and disabling or subjecting the person to unacceptable distress. It is also indicated as a treatment for the management of acute alcohol withdrawal syndrome. When combined with Amitriptyline (known as Limbitrol), it can be used to treat new daily persistent headache disorder.〔http://www.headaches.org/education/Medications/Limbitrol〕
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